Can patients with asthma take indomethacin tablets?

Jan 15, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, patients with asthma usually cannot use Indomethacin tablets. Indomethacin tablets are non-steroidal anti-inflammatory drugs (NSAIDs) that have antipyretic, analgesic, and anti-inflammatory effects. They are primarily used for soft tissue injuries and inflammation, fever reduction, and relieving symptoms such as pain and swelling associated with arthritis. However, this medication poses certain risks for patients with asthma.

Generally, asthma patients should not use Indomethacin tablets. The detailed explanation is as follows:

Indomethacin tablets are non-steroidal anti-inflammatory drugs (NSAIDs) that have antipyretic, analgesic, and anti-inflammatory effects. They are primarily used to treat soft tissue injuries and inflammation, fever, and to relieve symptoms such as pain and swelling associated with arthritis. However, this medication poses certain risks for asthma patients.

Although Indomethacin tablets have a certain bronchodilating effect and may help alleviate symptoms such as coughing and wheezing in asthma patients, the drug also strongly inhibits the synthesis of prostaglandin E2, which may cause bronchial smooth muscle contraction, thereby worsening asthma symptoms. Therefore, asthma patients are advised not to use Indomethacin tablets. Additionally, Indomethacin tablets may cause adverse reactions such as nausea, vomiting, dizziness, headache, anxiety, and insomnia.

If asthma patients develop fever, Indomethacin tablets should be used with caution. This medication may reduce the sensitivity of the body's temperature-regulating center, thereby affecting the normal heat dissipation process and potentially causing either abnormally high or low body temperature. Meanwhile, asthma patients should actively avoid known allergens and other triggering factors to reduce the risk of acute attacks.

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