How long is the shelf life of povidone-iodine?

Under normal conditions, the shelf life of povidone-iodine is usually 24 months when unopened, and it should be used within 1-2 months after opening, with a typical expiration period of 1-2 months. However, if the povidone-iodine becomes contaminated, it may become ineffective immediately. Detailed explanation is as follows:

When stored properly in a cool, dry, and light-protected place, unopened povidone-iodine generally has a shelf life of 24 months, which is two years. However, the shelf life of povidone-iodine produced by different manufacturers should follow the instructions indicated on the product label.

Once the povidone-iodine is opened, its shelf life will be significantly shortened. This is because after opening, the povidone-iodine comes into contact with air, and the iodine component gradually volatilizes, causing a decrease in solution concentration, thereby affecting its disinfecting effectiveness. Generally, opened povidone-iodine should be used promptly and preferably consumed within one month. If the bottle cap can be tightened promptly after each use, the shelf life may be somewhat extended, but it is generally not recommended to use it beyond two months.

If the bottle cap is not tightened properly after opening, or if the solution becomes contaminated, the povidone-iodine may become immediately ineffective. Therefore, when using povidone-iodine, it is important to maintain its cleanliness and sterility.

Thus, during the use of povidone-iodine, it is important to maintain aseptic practices and avoid inserting contaminated swabs or gauze into the remaining solution in the bottle, to prevent contaminating the entire bottle of povidone-iodine.