What does it mean if prealbumin levels are low in liver function tests?

Jan 24, 2025 Source: Cainiu Health
Dr. Gao Jun
Introduction
In general, a low level of prealbumin in liver function tests indicates that the patient may have liver dysfunction or malnutrition. It is recommended to maintain a healthy diet and ensure adequate intake of high-quality proteins, such as lean meat, eggs, and milk, to support normal protein synthesis. At the same time, avoid不良 habits such as长期熬夜 (long-term sleep deprivation), excessive fatigue, misuse of medications, and alcohol consumption.

Generally, a low level of prealbumin in liver function tests indicates that the patient may have liver dysfunction or malnutrition. Detailed analysis is as follows:

Prealbumin is a protein synthesized by liver cells. Due to its relatively short half-life in plasma, changes in its concentration can sensitively reflect the liver's synthetic capacity and the body's nutritional status. When liver function is impaired, such as in diseases like hepatitis, cirrhosis, or liver cancer, the ability of liver cells to synthesize prealbumin decreases, leading to lower plasma prealbumin levels. Additionally, malnutrition and insufficient protein intake can also affect prealbumin synthesis, causing its levels to drop.

Maintaining a healthy diet and ensuring adequate intake of high-quality proteins, such as lean meats, eggs, and milk, is important for maintaining normal protein synthesis. At the same time, avoid不良 habits such as chronic sleep deprivation, excessive fatigue, drug abuse, and alcohol consumption, all of which may damage the liver.