What causes excessively high levels of transaminases in the blood?

Generally, elevated levels of transaminase in the blood may be related to causes such as strenuous exercise, excessive fatigue, fatty liver disease, drug-induced liver injury, and viral hepatitis. It is recommended to seek timely medical attention and follow a doctor's guidance for treatments such as general therapy or medication. Detailed analysis is as follows:

1. Strenuous Exercise

Following strenuous exercise, muscle cells may experience a certain degree of damage, leading to the release of transaminase into the bloodstream and causing a mild increase in serum transaminase levels. It is recommended to avoid prolonged, high-intensity exercise, engage in moderate physical activity, and ensure adequate rest.

2. Excessive Fatigue

Long-term overexertion can increase the burden on the liver and impair normal metabolic functions of the liver, preventing effective metabolism of transaminase, thus causing elevated levels. It is recommended to maintain a regular sleep-wake schedule and avoid staying up late.

3. Fatty Liver Disease

Fatty liver disease is usually caused by factors such as excessive nutrition and genetic predisposition. When excessive fat accumulates within liver cells, it causes liver cell damage, which leads to elevated transaminase levels. Symptoms often include discomfort in the upper right abdomen, fatigue, and poor appetite. It is recommended to follow medical advice for treatment with medications such as simvastatin tablets, atorvastatin calcium tablets, and inosine tablets.

4. Drug-induced Liver Injury

Drug-induced liver injury is typically caused by drug side effects. Some drugs may produce toxic metabolites during metabolism in the liver, or the drugs themselves may have direct toxicity to liver cells, causing damage and subsequent elevation of transaminase levels. Symptoms generally include nausea, vomiting, and jaundice. Treatment under medical guidance may involve medications such as Hugan tablets, compound glycyrrhizin capsules, and enteric-coated capsules of diammonium glycyrrhizinate.

5. Viral Hepatitis

Viral hepatitis is usually caused by viral infection. Hepatitis viruses infect liver cells, triggering inflammatory responses and damaging liver cells, which leads to the release of transaminase into the bloodstream. Additional symptoms may include weight loss, fatigue, and jaundice. Treatment under a doctor's recommendation may involve medications such as entecavir dispersible tablets, tenofovir disoproxil fumarate tablets, and diammonium glycyrrhizinate injection.

In daily life, it is advisable to consume moderate amounts of foods rich in vitamins and amino acids, such as glutinous rice, apples, and milk, while avoiding preserved foods, processed foods, and mold-contaminated foods to maintain liver health.