What are the medications that inhibit scar hyperplasia?

Generally speaking, scars refer to cicatrix. Medications that inhibit scar hyperplasia include scar removal ointment, tretinoin cream, asiaticoside cream, low molecular weight heparin sodium gel, and mucopolysaccharide polysulfate cream. The detailed analysis is as follows:

1. Scar Removal Ointment

Scar removal ointment is mainly composed of ingredients such as peach seed, Brucea javanica seed, and borneol. It has the effects of softening and dispersing hard masses and promoting blood circulation to remove scars. It can be used as an adjunctive treatment for hypertrophic scars caused by burns, scalds, and trauma.

2. Tretinoin Cream

This medication can be used for scar treatment. Its primary mechanism is to promote local blood circulation and reduce inflammatory responses, thereby inhibiting scar hyperplasia. It can penetrate into the deeper layers of the skin and exert anti-inflammatory and anti-proliferative effects.

3. Asiaticoside Cream

The main component is total glycosides of centella asiatica, which promotes wound healing and inhibits scar hyperplasia. Asiaticoside can stimulate the regeneration and repair of skin cells while inhibiting excessive proliferation of fibroblasts and excessive synthesis of collagen fibers, thus reducing the degree of scar hyperplasia.

4. Low Molecular Weight Heparin Sodium Gel

This medication contains multiple ingredients, including heparin sodium, allantoin, and onion extract. It has anti-inflammatory, anti-proliferative, scar-softening, and moisturizing effects. Allantoin can soften the stratum corneum and promote drug penetration, while onion extract has anti-inflammatory and antioxidant effects, helping to alleviate inflammatory responses and oxidative stress damage in scars.

5. Mucopolysaccharide Polysulfate Cream

Mucopolysaccharide polysulfate is a natural polysaccharide compound with anti-inflammatory, antithrombotic, and tissue repair-promoting properties. In scar treatment, mucopolysaccharide polysulfate cream can reduce inflammation at the scar site, inhibit fibroblast proliferation and collagen fiber synthesis, thereby alleviating scar hyperplasia and hardening.

In daily life, to prevent scar hyperplasia, proper wound care should be emphasized. After injury, promptly clean the wound to avoid infection. Use appropriate disinfectants and follow medical advice for dressing and changing medication. At the same time, maintain a balanced diet, ensuring sufficient intake of vitamins and minerals, which contributes to skin health and repair.