Can third-generation IVF screen for all diseases?

Feb 13, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, the third-generation IVF technology cannot screen for all diseases. Third-generation IVF technology, also known as preimplantation genetic diagnosis or preimplantation genetic screening, can detect various genetic disorders, including single-gene inherited diseases, chromosomal structural abnormalities, and chromosomal numerical abnormalities. However, its screening scope does not cover all diseases.

Generally, the third-generation IVF (in vitro fertilization) technology cannot screen for all diseases. A detailed explanation is as follows:

The third-generation IVF technology, also known as preimplantation genetic diagnosis or preimplantation genetic screening, can detect various genetic diseases, including single-gene disorders, chromosomal structural abnormalities, and chromosomal numerical abnormalities. However, its screening scope is limited and does not cover all diseases. Due to technological limitations and disease complexity, this technology cannot detect all types of diseases, especially certain polygenic disorders and complex diseases.

In daily life, for families with a risk of hereditary diseases, it is recommended to undergo genetic counseling before planning pregnancy to understand personal and family medical history and potential genetic risks. Additionally, both partners should maintain a balanced diet, engage in moderate exercise, ensure adequate sleep, and avoid exposure to harmful substances to promote overall health and fertility.