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It is generally possible to make up for a missed dose of long-acting insulin, but this should be done under the guidance of a doctor.

If a patient realizes they have missed a dose of long-acting insulin shortly afterward, for example within a few hours, and their blood sugar levels have not yet risen significantly, the missed dose can usually be taken as a makeup dose. When making up the dose, the insulin amount should be adjusted according to medical advice to avoid excessive insulin that could lead to hypoglycemia. In such cases, taking the makeup dose helps maintain blood glucose control and prevents complications caused by high blood sugar. After taking the makeup dose, it is important to monitor blood glucose levels and ensure that the next injection is scheduled no earlier than 20 hours after the makeup dose.

If more than 24 hours has passed before realizing the missed dose of long-acting insulin, blood glucose levels may have already changed significantly. At this point, the dose should not be made up independently. Instead, the patient should promptly visit the hospital for blood glucose testing, and the doctor will adjust the insulin dosage accordingly. During the use of long-acting insulin, to avoid missed or forgotten injections, patients are advised to set alarms, timers, or use reminder notes to help remember their injections.

In addition, after taking a makeup dose, patients should make every effort to avoid missing injections again. Maintaining regular lifestyle habits and medication routines can help achieve better diabetes control.