Can fibrates treat high triglycerides?
Feb 20, 2025
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Hypertriglyceridemia usually refers to high triglyceride levels in the blood. Fibrates can treat hypertriglyceridemia and it is recommended to seek timely medical attention and follow the guidance of a physician for treatment. If you have hypertriglyceridemia, you may use fibrates as directed by your doctor. During treatment, it is also important to maintain healthy lifestyle habits, including a balanced diet, regular exercise, and periodic monitoring of lipid levels.
Hypertriglyceridemia generally refers to elevated levels of triglycerides in the blood. Under normal circumstances, fibrate medications can treat hypertriglyceridemia, and patients are advised to seek timely medical consultation and follow the guidance of a physician for appropriate treatment. Detailed explanations are as follows:
Fibrates are fibric acid derivatives and are commonly used clinically for the treatment of hyperlipidemia, particularly suitable for treating hypertriglyceridemia. Fibrates primarily activate peroxisome proliferator-activated receptor alpha (PPAR-alpha), thereby increasing the activity of lipoprotein lipase and reducing triglyceride levels in the blood. For patients with significantly elevated triglyceride levels, physicians may prescribe fibrates to reduce the risk of cardiovascular disease. Additionally, fibrates can lower total cholesterol and low-density lipoprotein cholesterol levels while mildly increasing high-density lipoprotein cholesterol levels, thus comprehensively improving blood lipid profiles.
If diagnosed with hypertriglyceridemia, patients can use fibrates as directed by their physician. During treatment, maintaining healthy lifestyle habits is also essential, including balanced nutrition, regular physical activity, and periodic monitoring of lipid levels.
