Can patients with liver and kidney disease take sleeping pills?

Feb 21, 2025 Source: Cainiu Health
Dr. Zhang Baohua
Introduction
If patients with liver or kidney disease have only mild impairment of liver and kidney function, and physicians determine that their bodies can still metabolize and excrete medications, certain hypnotics that are not entirely dependent on liver or kidney metabolism, or that impose less burden on these organs, may be selected under strict medical supervision. For example, some non-benzodiazepine medications may be more suitable for these patients.

  If patients with liver or kidney disease only have mild abnormalities in liver or kidney function, they generally can take sleeping pills, but should follow medical advice regarding their use. If the patient's liver or kidney function is severely impaired, they typically should not take sleeping pills. If the body experiences any discomfort, it is recommended to seek medical attention at a hospital promptly and then follow the doctor's instructions for treatment.

  If a patient with liver or kidney disease has only minor impairment of liver or kidney function, and a physician assesses that the patient can metabolize and excrete medication, then under strict medical supervision, certain sleeping pills that are metabolized through pathways not entirely dependent on the liver or kidneys or that impose a lower burden on these organs may be selected. For example, certain non-benzodiazepine medications may be more suitable for these patients. Under a physician's guidance, short-term and low-dose usage carries relatively lower risk.

  However, it should be noted that patients with severe liver or kidney dysfunction have reduced capacity for drug metabolism and excretion. Taking sleeping pills may further burden the liver and kidneys, causing drug accumulation in the body and potentially triggering adverse reactions. Therefore, these patients should avoid taking sleeping pills as much as possible. If a patient is allergic to any ingredients in sleeping pills, administration may provoke allergic reactions such as rash, itching, or difficulty breathing. Thus, patients allergic to components of sleeping pills should not take them.

  In daily life, patients should follow medical guidance to use medications properly. Improving sleep quality can also be achieved naturally through methods such as enhancing the sleep environment, maintaining regular sleep schedules, and receiving psychological counseling.