Can patients with hepatic and renal insufficiency use antidiabetic drugs?

Whether patients with impaired liver and kidney function can use hypoglycemic drugs needs to be determined based on individual circumstances. If the condition is mild, these medications are generally usable; however, if the condition is severe, their use may not be advisable. If any discomfort occurs, timely medical consultation is recommended, and treatment should be conducted under the guidance of a physician. Detailed explanations are as follows:

For patients with mild liver or kidney dysfunction, certain hypoglycemic drugs can be safely used by adjusting the dosage or monitoring drug responses. During use, it is important to follow medical advice regarding dosage adjustments and to regularly monitor kidney function and blood glucose levels.

If liver and kidney functions are severely compromised, the body's ability to metabolize and excrete drugs is significantly reduced. In such cases, using hypoglycemic drugs may increase drug toxicity, further burden the liver and kidneys, and potentially lead to drug accumulation and poisoning.

Patients with impaired liver and kidney function must use hypoglycemic drugs only under the supervision of a physician and must not self-administer medication or alter their treatment plan. In addition to pharmacological treatment, individuals with liver and kidney dysfunction should also pay attention to dietary control, consuming appropriate amounts of low-sugar, low-fat, high-fiber foods to reduce the burden on the liver and kidneys.