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What are the side effects of Fenbid?

Mar 09, 2025 Source: Cainiu Health
Dr. Bai Hongmei
Introduction
In general, Fenbid refers to ibuprofen sustained-release capsules. Possible side effects of ibuprofen sustained-release capsules may include gastrointestinal reactions, liver and kidney function damage, nervous system reactions, hematologic system reactions, and cardiovascular system effects. When using ibuprofen sustained-release capsules, patients should follow medical advice for medication, pay attention to physical reactions, and seek timely medical attention for side effect management.

Generally speaking, Fenbid refers to ibuprofen sustained-release capsules. Possible side effects of ibuprofen sustained-release capsules include gastrointestinal reactions, liver and kidney function damage, nervous system reactions, blood system reactions, and elevated blood pressure. Detailed analysis is as follows:

1. Gastrointestinal Reactions

The medication may inhibit the synthesis of prostaglandins in the gastric mucosa, weakening its protective effect and making the gastric mucosa more susceptible to damage by gastric acid. Symptoms such as nausea, vomiting, indigestion, and stomach pain may occur. Long-term or excessive use can lead to serious problems such as gastric ulcers and gastrointestinal bleeding.

2. Liver and Kidney Function Damage

Ibuprofen sustained-release capsules are primarily metabolized by the liver and excreted through the kidneys. When taken in excessive doses or by individuals with pre-existing liver or kidney dysfunction, the metabolism and excretion of the drug may be impaired, leading to accumulation of the drug and its metabolites in the body. This may cause toxic effects on liver and kidney cells, damaging liver and kidney function.

3. Nervous System Reactions

Ibuprofen sustained-release capsules may affect the normal functioning of the nervous system by disrupting the balance of neurotransmitters or interfering with neural signal transmission. Additionally, the drug may have certain effects on cerebral blood vessels, influencing cerebral blood supply and nerve regulation, thereby causing nervous system symptoms such as dizziness, headache, drowsiness, tinnitus, and even episodes of syncope.

4. Blood System Reactions

Ibuprofen sustained-release capsules may suppress the bone marrow's hematopoietic function, affecting the production of blood cells such as white blood cells and platelets. Additionally, the drug may inhibit platelet aggregation, weakening their ability to stop bleeding and thus increasing the tendency for bleeding.

5. Elevated Blood Pressure

Ibuprofen sustained-release capsules may inhibit the activity of cyclooxygenase, thereby reducing prostaglandin synthesis. Prostaglandins play a role in dilating blood vessels and regulating blood pressure. With decreased prostaglandin synthesis, vasoconstrictive effects become relatively stronger, potentially leading to elevated blood pressure.

When using ibuprofen sustained-release capsules, patients should follow medical advice, pay attention to bodily reactions, and seek timely medical attention to manage any side effects.

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