Is it effective for patients with urticaria to receive immunoglobulin injections?

Generally speaking, if urticaria patients have compromised immune function or require temporary immune enhancement to assist treatment, immunoglobulin injections may be considered, although the effectiveness varies from person to person. However, immunoglobulin should be used with caution in patients with known allergy risks or clear allergens. If any abnormalities occur, timely medical consultation is recommended. Detailed analysis is as follows:

Immunoglobulin has dual therapeutic effects of immune replacement and immune regulation. It can enhance the patient's immunity, thereby improving resistance to pathogens, and help alleviate symptoms of urticaria by modulating immunoglobulin E (IgE) or its high-affinity receptor function. To some extent, immunoglobulin can suppress allergic reactions and serve as an adjunctive treatment for urticaria caused by allergies or infections.

However, immunoglobulin contains various heterologous protein components, which may act as new allergens and thereby worsen urticaria symptoms. Furthermore, since immunoglobulin cannot provide allergen-specific treatment, its use may lead to persistent or worsening symptoms if urticaria is triggered by specific foods, medications, or other external factors. Additionally, some patients may experience adverse reactions such as fever, dizziness, or rash after receiving immunoglobulin injections, which could exacerbate urticaria symptoms or cause other discomforts.

Patients with urticaria should follow individualized treatment plans as advised by their physicians. Medications such as ephedrine diphenhydramine tablets, cetirizine hydrochloride tablets, or fexofenadine hydrochloride tablets may be used under medical guidance. It is also important to avoid known allergens to reduce the risk of urticaria flare-ups.