What are the effects of Ampicillin Sodium and Sulbactam Sodium?

Generally, Ampicillin Sodium and Sulbactam Sodium for injection may have functions such as inhibiting bacterial cell wall synthesis, enhancing antimicrobial activity against drug-resistant bacteria, treating respiratory tract infections, managing urogenital tract infections, and addressing skin and soft tissue infections.

1. Inhibition of Bacterial Cell Wall Synthesis

Ampicillin Sodium and Sulbactam Sodium for injection can target key stages in the synthesis of the bacterial cell wall, inhibit the activity of transpeptidase, hinder the cross-linking of peptidoglycan, and prevent normal cell wall formation. The integrity of the bacterial cell wall is compromised, causing internal osmotic pressure imbalance, making it difficult for bacteria to maintain their normal shape, ultimately leading to bacterial death, and effectively combating various Gram-positive and Gram-negative bacteria.

2. Enhanced Antimicrobial Activity Against Drug-Resistant Bacteria

Ampicillin Sodium and Sulbactam Sodium for injection, as a β-lactamase inhibitor, can tightly bind to β-lactamase produced by bacteria. Many drug-resistant bacteria rely on β-lactamase to destroy β-lactam antibiotics, rendering them inactive. This medication protects ampicillin from enzymatic degradation. The combination enhances antimicrobial activity against drug-resistant bacteria producing β-lactamase, effectively inhibiting or killing previously resistant bacteria.

3. Treatment of Respiratory Tract Infections

Streptococcus pneumoniae and Haemophilus influenzae commonly cause respiratory tract infections. Ampicillin Sodium and Sulbactam Sodium for injection reach the infected areas of the respiratory tract via the bloodstream, inhibiting or killing these pathogens, reducing inflammatory responses, alleviating symptoms such as coughing, sputum production, fever, and breathing difficulties, promoting recovery of respiratory function, and accelerating improvement of the condition.

4. Management of Urogenital Tract Infections

Escherichia coli and Neisseria gonorrhoeae are common pathogens causing urogenital tract infections. Ampicillin Sodium and Sulbactam Sodium for injection reach the urogenital tract via the bloodstream, exerting antimicrobial effects, inhibiting bacterial growth and reproduction, improving symptoms such as frequent urination, urgency, painful urination, and genital manifestations like abnormal discharge and itching, helping patients regain urogenital health.

5. Treatment of Skin and Soft Tissue Infections

Staphylococcus aureus and hemolytic streptococci easily cause skin and soft tissue infections. The medication distributes via the bloodstream to infected skin and surrounding soft tissues, inhibiting bacterial growth, eliminating pathogens, controlling inflammation, reducing symptoms such as redness, pain, and fever, promoting wound healing, preventing infection spread to adjacent tissues, and maintaining skin integrity.

Ampicillin Sodium and Sulbactam Sodium for injection have various functions and should be used under a physician's guidance. If adverse symptoms occur during use, patients should promptly inform their doctor and discontinue the medication.