Can Tranexamic Acid Tablets be used for surgical hemostasis?

Tranexamic acid tablets are commonly used for hemostasis during surgical procedures. However, they are generally not recommended in cases of thrombosis tendency or certain specific complications. If in doubt, it is advisable to seek medical consultation in advance. Detailed analysis is as follows:

Tranexamic acid tablets work by inhibiting the activity of plasmin, preventing the degradation of fibrin, promoting thrombus formation, thereby reducing or stopping bleeding. This medication is commonly applied during various surgeries such as orthopedic surgery, cardiac surgery, and cranial surgery. It helps reduce bleeding at the surgical site, decreases the need for blood transfusions, and lowers the risks associated with transfusions, thus facilitating successful surgical outcomes and postoperative recovery.

However, caution is required when using tranexamic acid tablets for surgical hemostasis in patients with a tendency for thrombosis or certain specific complications. Patients with a predisposition to thrombosis may face an increased risk of thrombus formation when using tranexamic acid, which could lead to more severe complications. Additionally, tranexamic acid should be used with caution in patients with hemophilia or those experiencing massive hematuria due to pyelocalyceal parenchymal lesions, as it might exacerbate bleeding or cause other adverse reactions.

Moreover, although tranexamic acid is generally well tolerated, some adverse reactions may occur, such as nausea, vomiting, and headache. If any discomfort occurs during use, seek medical attention promptly.