What causes flaccid paralysis in the limbs?

Mar 19, 2025 Source: Cainiu Health
Dr. Chen Jian
Introduction
In general, flaccid paralysis of the limbs may be caused by prolonged sitting or standing, excessive fatigue, malnutrition, myelitis, hypokalemia, and other factors. Symptomatic management such as general care and medication may be needed. If flaccid paralysis of the limbs occurs, immediate rest is necessary, and forced limb movement should be avoided to prevent injuries from falls due to weakness.

Generally, flaccid paralysis of the limbs may be caused by prolonged sitting or standing, excessive fatigue, malnutrition, myelitis, hypokalemia, and other factors. Symptomatic management such as general treatment and drug therapy may be needed. If discomfort occurs, it is recommended to seek medical advice promptly and receive appropriate treatment under a doctor's guidance. Detailed explanations are as follows:

1. Prolonged Sitting or Standing

Prolonged sitting or standing can impair blood circulation in the lower limbs, leading to muscle hypoxia and accumulation of metabolic waste, which may cause flaccid paralysis of the limbs and may be accompanied by heaviness and numbness in the lower limbs. It is recommended to change posture regularly, engage in appropriate limb activity to promote blood circulation, and wear compression stockings if necessary.

2. Excessive Fatigue

Muscles produce metabolic byproducts such as lactic acid during exercise. If exercise duration is too long or intensity too high, excessive accumulation of lactic acid can lead to muscle fatigue and weakness. It is recommended to rest appropriately, perform local massage and hot compresses to promote lactic acid metabolism and muscle recovery.

3. Malnutrition

Deficiency in essential nutrients, such as vitamin B12 and folic acid, may affect normal nervous system function and potentially cause symptoms of flaccid limb paralysis and weakness, possibly accompanied by anemia, loss of appetite, and weight loss. A balanced diet rich in vitamin B12 and folic acid, such as meat, eggs, and leafy vegetables, is recommended.

4. Myelitis

Myelitis is mainly caused by viral or bacterial infections, autoimmune reactions, or other factors that lead to inflammatory lesions in the spinal cord. Spinal cord edema and inflammation caused by myelitis can compress nerve roots within the spinal cord, impairing nerve signal transmission and causing limb weakness, possibly accompanied by fever, urinary retention, and sensory abnormalities. It is recommended to take medications such as calcium carbonate chewable tablets, potassium chloride extended-release tablets, and mecobalamin capsules under a doctor's guidance.

5. Hypokalemia

Hypokalemia is primarily caused by insufficient potassium intake, excessive potassium loss, or abnormal distribution of potassium between intracellular and extracellular compartments. Potassium ions help maintain normal neuromuscular function; hypokalemia can interfere with signal transmission at neuromuscular junctions, causing muscle weakness, possibly accompanied by palpitations, nausea, and vomiting. It is recommended to take medications such as potassium chloride extended-release tablets, potassium chloride injections, and potassium glutamate for injection under a doctor's guidance.

If flaccid paralysis of the limbs occurs, immediate rest is necessary. Avoid forcibly moving the limbs to prevent injury due to weakness and risk of falling.