What are the serious side effects of Yanhuning?

Mar 19, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Yanhuining is commonly used for the treatment of viral pneumonia and upper respiratory tract infections, but it has serious side effects, such as allergic reactions, gastrointestinal reactions, hematologic system reactions, liver function damage, and skin tissue necrosis. It can cause significant harm to the human body and may even affect physical activities. Therefore, it must be used strictly according to medical instructions, and self-medication should be avoided.

Under normal circumstances, Yanhuning (Sodium Cantharidate) is commonly administered as an injection and is frequently used in the treatment of viral pneumonia and viral upper respiratory tract infections. Relatively serious side effects of Yanhuning include allergic reactions, gastrointestinal reactions, hematologic system reactions, liver function damage, and skin tissue necrosis. If any discomfort occurs, prompt medical attention is necessary. Detailed analysis is as follows:

1. Allergic Reactions

If an individual is allergic to any component of Yanhuning, its use may trigger an allergic reaction, such as skin rashes, itching, and in severe cases, difficulty breathing and swelling. The drug should be discontinued immediately, and if necessary, treatment under medical guidance may include calamine lotion, cetirizine hydrochloride tablets, or loratadine capsules.

2. Gastrointestinal Reactions

Yanhuning may irritate the gastrointestinal mucosa, leading to symptoms such as nausea, vomiting, abdominal pain, and diarrhea. It is recommended to increase water intake appropriately during treatment to accelerate metabolism. The diet should be light, avoiding spicy or irritating foods.

3. Hematologic System Reactions

Long-term use of Yanhuning may cause bone marrow suppression, resulting in reduced white blood cell and platelet counts. In such cases, the dosage should be adjusted promptly, and if necessary, the drug should be discontinued as directed by a physician.

4. Liver Function Damage

Components of Yanhuning may also damage the liver. Prolonged use may lead to abnormal liver metabolism and impaired liver function, manifesting as jaundice and fatigue. Patients experiencing such symptoms may, under medical guidance, use hepatoprotective medications such as Hugan Pian (Liver-Protecting Tablets) or compound glycyrrhizin tablets.

5. Skin Tissue Necrosis

Skin tissue necrosis is relatively rare but may occur in some patients who use Yanhuning long-term or in large doses. Symptoms may include skin swelling and bleeding, and in severe cases, mobility may be affected. The drug should be discontinued promptly as directed by a physician, and alternative medications should be considered.

It is recommended that Yanhuning be used strictly according to the physician's instructions to avoid self-medication. Additionally, adequate rest should be ensured during treatment, and sleep deprivation should be avoided as it may affect immunity.