What are the side effects of deep-sea fish oil?

Mar 19, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
In general, deep-sea fish oil is a dietary supplement that is rich in ω-3 polyunsaturated fatty acids, which help regulate blood lipids, improve vision, and provide other benefits. Possible side effects may include gastrointestinal discomfort, bad breath and a fishy aftertaste, increased risk of bleeding, impaired blood sugar control, and increased burden on the liver. To reduce the side effects of deep-sea fish oil, it is recommended to consult a physician before taking it.

Generally speaking, deep-sea fish oil is a dietary supplement. Its possible side effects include gastrointestinal discomfort, bad breath and a fishy odor, increased risk of bleeding, impaired blood sugar control, and increased burden on the liver. Detailed analysis is as follows:

  

  1. Gastrointestinal Discomfort

Because the fatty acids in fish oil may irritate the gastrointestinal tract and affect its normal digestive and absorptive functions, some individuals might experience symptoms such as nausea, vomiting, diarrhea, and indigestion. These symptoms may be more pronounced when fish oil is taken on an empty stomach.

  2. Bad Breath and Fishy Odor

During the metabolism of fish oil components in the body, certain substances with a distinctive odor may be excreted through breath, potentially causing an unpleasant fishy smell or bad breath.

  3. Increased Risk of Bleeding

Omega-3 fatty acids in deep-sea fish oil have anticoagulant properties. Long-term or excessive consumption may inhibit platelet aggregation and prolong bleeding time. For individuals taking anticoagulant medications or those with bleeding disorders, this could increase the risk of bleeding, such as nosebleeds, gum bleeding, or difficulty in stopping wound bleeding.

  4. Impaired Blood Sugar Control

Deep-sea fish oil may have some impact on blood glucose levels. For individuals with diabetes or unstable blood sugar levels, it may interfere with normal glycemic control. Blood glucose levels should be closely monitored during fish oil supplementation, and the dosage of hypoglycemic medications may need adjustment if necessary.

  5. Increased Burden on the Liver

Components of deep-sea fish oil need to be metabolized in the liver. Prolonged and excessive consumption of fish oil may increase the liver's workload. For individuals with pre-existing liver dysfunction, this could lead to abnormal liver function indicators, such as elevated transaminase levels.

  To minimize the side effects of deep-sea fish oil, it is recommended to consult a physician or nutritionist before taking it, and to determine whether it is suitable based on individual health status and specific needs.

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