Can Cornus officinalis with seeds be soaked in alcohol for consumption?
Generally, Cornus officinalis with pits can be used to make medicinal wine. However, if a better taste is desired, it is not recommended to use Cornus officinalis with pits for wine infusion. Detailed explanation is as follows:

Cornus officinalis has functions of nourishing the liver and kidneys and restraining seminal emission and slipping. After being infused in wine, its medicinal effects can be enhanced. It is suitable for symptoms such as liver and kidney insufficiency, soreness and weakness of the waist and knees, and seminal emission. The presence of pits in Cornus officinalis will not affect its medicinal effects.
However, the pits of Cornus officinalis may carry a certain bitterness, which could influence the taste of the wine. If a purer, sweeter flavor is desired, it is recommended to use pit-free Cornus officinalis. In rare cases, the pits might carry the risk of contamination or deterioration.
When preparing Cornus officinalis wine, ensure the quality and reliable source of the Cornus officinalis, and avoid using expired or deteriorated Cornus officinalis.
References
[1] Wang Jiajun, Wang Zeping, Wang Xuelian, et al. Research progress on chemical constituents and pharmacological effects of Cornus officinalis [J]. Chinese Traditional and Herbal Drugs, 2025, 56(03): 1088-1103.
[2] Zhang Yanyan, Huang Yigang. Research on the biological activity of Cornus officinalis [J]. Modern Food, 2024, 30(20): 76-78.