Can Lycium barbarum (Goji berry) be used as a substitute for Cornus officinalis (Japanese cornel)?
Wolfberry fruits generally cannot fully replace Cornus officinalis (Chinese dogwood), and it is important to use medications under the guidance of a physician.

Under normal circumstances, wolfberry fruits cannot completely substitute for Cornus officinalis, nor can the two be used interchangeably at will. The choice mainly depends on the specific purpose of use and health condition. If considering only general health benefits such as nourishing the liver and kidneys, improving vision, and relieving fatigue, wolfberry fruits can be used as an alternative to Cornus officinalis, as both have certain nourishing effects and share similarities in enhancing immunity and anti-aging properties.
Although wolfberry fruits and Cornus officinalis have some overlapping functions, such as nourishing the liver and kidneys, wolfberry fruits are relatively weaker in terms of astringent and anti-sweating effects, strengthening the heart, and lowering blood lipids. Therefore, when these specific therapeutic effects are required, wolfberry fruits cannot fully replace Cornus officinalis. Wolfberry fruits are more suitable for improving sleep quality, beauty care, and reducing blood sugar levels. In terms of nourishing the liver and kidneys, Cornus officinalis has a more significant effect, especially for conditions such as kidney deficiency with seminal emission and spontaneous sweating.
It is recommended to choose appropriate medicinal materials under the guidance of a qualified traditional Chinese medicine practitioner for health regulation or treatment, avoiding self-substitution of herbs to prevent potential adverse effects on health.