Which blood test indicator shows Type A or Type B influenza?
Generally speaking, "Jia Liu" refers to influenza A, and "Yi Liu" refers to influenza B. When testing for influenza A or B, blood tests mainly examine the white blood cell count in the complete blood count (CBC), lymphocyte count in the CBC, C-reactive protein (CRP), procalcitonin (PCT), and influenza virus-specific antibodies. Detailed explanations are as follows:

1. White Blood Cell Count in Complete Blood Count
During infection with influenza A or B, the white blood cell count is usually normal or decreased. This is because the immune response triggered by the viral infection shifts the immune system's focus toward fighting the virus, thereby altering the production and release patterns of white blood cells. Consequently, the peripheral blood white blood cell count does not significantly increase and may even decrease due to factors such as viral suppression of bone marrow hematopoietic function.
2. Lymphocyte Count in Complete Blood Count
Patients may experience a decrease in lymphocyte count. The influenza virus primarily invades respiratory epithelial cells and also affects the function and number of lymphocytes. Viral infection leads to lymphocyte damage and increased apoptosis, resulting in a decline in peripheral blood lymphocyte count, which reflects the impact of the virus on the body's immune cells.
3. C-Reactive Protein (CRP)
CRP levels generally show a mild increase. CRP is an acute-phase reactant protein whose production by the liver increases during inflammation. After the human body is infected with influenza A or B virus, an inflammatory response is triggered, stimulating CRP synthesis. However, the degree of elevation is typically not as pronounced as during bacterial infection, making CRP a useful reference indicator for distinguishing between viral and bacterial infections.
4. Procalcitonin (PCT)
PCT is a glycoprotein without hormonal activity that significantly increases during systemic bacterial infections. Influenza A and B are viral infections, so PCT levels typically do not rise significantly. However, when influenza is complicated by bacterial infection, PCT levels may markedly increase, aiding in the assessment of possible co-infection.
5. Influenza Virus-Specific Antibodies
These include IgM and IgG antibodies. IgM antibodies are produced early in infection and generally can be detected 3-5 days after symptom onset, indicating a recent infection. IgG antibodies appear later, usually increasing around 10-15 days after infection and persisting for a longer duration in the body. They are useful for retrospective diagnosis and epidemiological investigations. Detecting these specific antibodies can assist in diagnosing infection with influenza A or B.
In daily life, attention should be paid to personal hygiene, frequent handwashing using soap or hand sanitizer, and thoroughly washing hands following the seven-step handwashing technique, especially after touching public items, before meals, and after using the toilet. Additionally, maintaining good indoor air circulation and regularly opening windows for ventilation can help reduce the likelihood of virus transmission.