What are the efficacy and functions of Pulsatilla (Baitouweng) in treating anal fistula?

When treating anal fistula, Pulsatilla (Baitouweng) can generally exert effects such as clearing heat and detoxifying, reducing swelling and discharging pus, antibacterial and anti-inflammatory actions, promoting tissue repair, and relieving pain. If there are any concerns, it is recommended to seek medical advice in advance. Detailed explanations are as follows:

1. Clearing Heat and Detoxifying: For redness, swelling, heat, pain, and thick pus caused by accumulation of damp-heat toxins around the anus, components such as Pulsatilla saponin in Pulsatilla can inhibit the spread of heat toxins, reduce local inflammatory responses, and are suitable for the acute exacerbation stage of anal fistula.

2. Reducing Swelling and Discharging Pus: For patients with pus accumulation inside the fistulous tract and recurrent rupture of the fistula opening, the bitter and cold properties of Pulsatilla can clear heat and remove dampness, promote pus drainage, reduce residual sinus tracts, and accelerate granulation tissue growth.

3. Antibacterial and Anti-inflammatory: Containing chlorogenic acid, caffeic acid, and other components, Pulsatilla can inhibit pathogens such as Escherichia coli and Staphylococcus aureus, reduce the risk of perianal infection, and assist in controlling chronic inflammation.

4. Promoting Tissue Repair: Polysaccharides in Pulsatilla can stimulate the proliferation of local fibroblasts, accelerate epithelialization of the ulcerated surface, improve the healing quality of the fistulous tract, and reduce the likelihood of recurrence.

5. Relieving Pain: By inhibiting prostaglandin synthesis and local vasodilation, Pulsatilla can alleviate anal heaviness, tenderness, and irritation pain during defecation, improving patient comfort.

However, it should be noted that Pulsatilla should be used in combination with surgical debridement or topical ointments. Sole reliance on traditional Chinese medicine alone should be avoided to prevent treatment delay. Spicy and greasy foods should also be avoided during medication.