What are the side effects of Fluticasone?

Generally speaking, Fluticasone refers to Azelastine Fluticasone Nasal Spray. Possible side effects of Azelastine Fluticasone Nasal Spray may include nasal dryness, nosebleeds, throat discomfort, allergic reactions, and adrenal cortical function suppression. If discomfort occurs, timely medical attention is recommended. Detailed analysis is as follows:

1. Nasal Dryness

Azelastine Fluticasone Nasal Spray, as a glucocorticoid medication, may affect the normal secretory function of the nasal mucosa while suppressing nasal inflammation. This can reduce mucosal secretions, leading to nasal dryness. Patients may feel discomfort inside the nasal cavity and sometimes experience mild itching.

2. Nosebleeds

When using Azelastine Fluticasone Nasal Spray, the medication may cause some irritation to the nasal mucosa, making it relatively fragile. If the capillaries beneath the mucosa are affected, they may rupture easily under external forces such as nose-blowing or picking, resulting in nosebleeds. Typically, the bleeding is minor and may appear as blood-streaked nasal discharge.

3. Throat Discomfort

When administering Azelastine Fluticasone Nasal Spray into the nose, some of the medication may drain into the throat through the nasal passages. This can irritate the throat mucosa, causing sensations of a foreign body, dryness, and possibly mild coughing, which may affect the patient's comfort and normal swallowing function.

4. Allergic Reaction

If an individual has hypersensitivity to any component of Azelastine Fluticasone Nasal Spray, the body's immune system may recognize the drug's components as foreign antigens after administration, triggering an immune response. Symptoms may include rash, itching, red papules or maculopapular eruptions on the skin, accompanied by significant itching, which can severely impact the patient's quality of life.

5. Adrenal Cortical Function Suppression

Long-term and excessive use of Azelastine Fluticasone Nasal Spray can lead to systemic absorption through the nasal mucosa into the bloodstream, thereby suppressing the hypothalamic-pituitary-adrenal axis. This may result in reduced endogenous corticosteroid secretion, causing symptoms such as fatigue, dizziness, and nausea. In severe cases, it can affect the body's stress response and immune function.

It is recommended to strictly follow medical instructions when using this medication, closely monitor any bodily reactions, and seek medical attention promptly if any discomfort occurs.