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How does right ventricular pressure affect tricuspid valve function?

Jun 05, 2025 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Under normal circumstances, the impact of right ventricular pressure on tricuspid valve function is mainly reflected in the closure status of the tricuspid valve, leading to tricuspid regurgitation, causing right ventricular dilation and hypertrophy, increasing right atrial pressure, and resulting in tricuspid stenosis. In the treatment of heart disease, it is necessary to closely monitor changes in right ventricular pressure and its effects on tricuspid valve function.

Generally, the impact of right ventricular pressure on tricuspid valve function is mainly reflected in the closing status of the tricuspid valve, causing tricuspid regurgitation, inducing right ventricular dilation and hypertrophy, increasing right atrial pressure, and leading to tricuspid stenosis. The specific details are as follows:

1. Tricuspid Valve Closure

When the right ventricle contracts, the increased pressure causes the tricuspid valve leaflets to close and seal the right ventricular orifice. The contraction of papillary muscles and the tension of the chordae tendineae ensure that the three closed leaflets do not prolapse into the right ventricle, effectively preventing blood from flowing back into the right atrium. This represents the positive influence of normal right ventricular pressure on tricuspid valve function.

2. Tricuspid Regurgitation

If right ventricular pressure remains elevated for a prolonged period, it may lead to incomplete closure of the tricuspid valve, resulting in blood flowing back into the right atrium during right ventricular systole, a condition known as tricuspid regurgitation. This situation increases the volume load on the right atrium, elevates pressure within the right atrium, and damages the normal function of the tricuspid valve.

3. Right Ventricular Dilation and Hypertrophy

Long-term elevation of right ventricular pressure leads to gradual thickening of the right ventricular wall and enlargement of the right ventricular cavity. These structural changes further affect the size and shape of the tricuspid annulus, worsening tricuspid insufficiency and creating a vicious cycle.

4. Increased Right Atrial Pressure

Elevated ventricular pressure is transmitted through the tricuspid valve to the right atrium, causing a corresponding increase in right atrial pressure. This not only causes right atrial dilation and hypertrophy but also affects venous return, leading to blood stasis in the systemic venous system and further increasing the burden on the right heart.

5. Tricuspid Stenosis

Although elevated right ventricular pressure primarily causes tricuspid regurgitation, in some cases, such as when the tricuspid valve leaflets thicken or adhere, it may also lead to tricuspid stenosis. A narrowed tricuspid valve hinders blood flow from the right atrium to the right ventricle, further exacerbating the elevation of right atrial pressure and symptoms of circulatory congestion.

In the treatment of heart diseases, it is necessary to closely monitor changes in right ventricular pressure and its impact on tricuspid valve function.

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