What is the maximum amount of blood one can donate?

Jun 24, 2025 Source: Cainiu Health
Dr. Liu Feng
Introduction
For first-time blood donors or those with a lighter body weight or weaker constitution, a blood donation volume of 200 ml is usually recommended. This amount has a relatively minor impact on the body, results in a smaller reduction of blood volume after donation, and is easier to recover from, thereby reducing the likelihood of experiencing adverse symptoms such as dizziness and fatigue, and ensuring the donor's health.

Generally speaking, there is no fixed maximum amount for blood donation. Whole blood donation typically ranges from 200 to 400 milliliters per session, while platelet apheresis usually involves donating one to two therapeutic units per session. The detailed explanation is as follows:

For first-time donors, or those with lower body weight or weaker physical conditions, a donation volume of 200 ml is usually recommended. This volume has a relatively smaller impact on the body, causes less reduction in blood volume after donation, and is easier to recover from, thereby reducing the likelihood of experiencing symptoms such as dizziness and fatigue and ensuring the donor's health.

If the donor is aged between 18 and 55 years, weighs at least 50 kg for males and 45 kg for females, and is in good health as determined by a medical examination—especially those who have donated blood multiple times and have strong physical adaptability—they may choose to donate 300 ml or 400 ml of whole blood, or one to two therapeutic units of platelets, based on personal preference and medical staff evaluation. However, after increasing the donation volume, the time required for recovery will be correspondingly longer.

Donors should fully understand their own physical condition before donation, strictly follow the requirements of the blood donation center and the guidance of medical staff. After donation, they should pay attention to rest and nutritional replenishment and seek help promptly if any discomfort occurs.