What are the medications for treating diabetic foot?
Jul 02, 2025
Source: Cainiu Health
Dr. Liu Feng
Introduction
Under normal circumstances, diabetic foot is one of the common and serious complications of diabetes, referring to foot infections, ulcers, or deep tissue damage caused by diabetic neuropathy, vascular disease, etc. Treatment may include medications such as amoxicillin clavulanate potassium tablets, beraprost sodium tablets, mecobalamin tablets, recombinant human epidermal growth factor gel, and aspirin enteric-coated tablets, as directed by a physician.
Generally, diabetic foot is one of the common and serious complications of diabetes, referring to foot infections, ulcers, or deep tissue destruction caused by diabetic neuropathy and vascular disease. Medications such as amoxicillin clavulanate potassium tablets, beraprost sodium tablets, mecobalamin tablets, recombinant human epidermal growth factor gel, and aspirin enteric-coated tablets may be used according to medical advice. A detailed explanation is as follows:
1. Amoxicillin Clavulanate Potassium Tablets
These tablets exert bactericidal effects by inhibiting bacterial cell wall synthesis and are effective against various Gram-positive and Gram-negative bacteria. They can be used to treat bacterial infections associated with diabetic foot. A drug sensitivity test should be conducted before medication, and the treatment should be adjusted based on the type of infecting bacteria. Adverse reactions such as gastrointestinal discomfort and allergic reactions may occur.
2. Beraprost Sodium Tablets
As a prostaglandin I2 derivative, this drug dilates blood vessels, inhibits platelet aggregation, improves blood circulation in the lower limbs, and increases blood supply to the feet. Common adverse reactions include headache and nausea. It should be used with caution in patients with severe heart, liver, or kidney dysfunction.
3. Mecobalamin Tablets
As an endogenous coenzyme B12, it participates in neuronal myelin sheath synthesis, promotes nerve cell repair and regeneration, and improves foot sensory abnormalities caused by diabetic peripheral neuropathy. Long-term administration is required; some patients may experience adverse reactions such as loss of appetite and rashes.
4. Recombinant Human Epidermal Growth Factor Gel
By binding to epidermal growth factor receptors, this gel promotes epidermal cell proliferation, differentiation, and migration, accelerating wound healing. It should be applied after cleaning the wound and should not be used simultaneously with disinfectants. It must be stored refrigerated to maintain its efficacy.
5. Aspirin Enteric-Coated Tablets
By inhibiting platelet cyclooxygenase, this medication reduces the production of thromboxane A2, thereby inhibiting platelet aggregation, preventing lower limb vascular thrombosis in patients with diabetic foot, and improving blood supply. Long-term use requires attention to adverse reactions such as gastrointestinal bleeding. It should be used cautiously in patients with gastric ulcers or bleeding tendencies.
Specific medication recommendations should be made under a physician's guidance, based on the patient's condition and individual differences. Self-medication should be avoided. At the same time, comprehensive measures such as blood glucose control and foot care should also be combined to enhance treatment effectiveness.
