Is thyroid cancer an in situ cancer?

Jul 08, 2025 Source: Cainiu Health
Dr. Yang Chuanjia
Introduction
Thyroid cancer is not necessarily carcinoma in situ; some cases are in situ, while others have already developed into invasive or metastatic disease. In the early stages of thyroid cancer, the lesion remains confined within the thyroid gland, without breaching the basement membrane, invading surrounding tissues, or spreading to lymph nodes or distant sites. At this stage, the cancer is classified as carcinoma in situ. In such cases, the lesion is localized, and surgical resection often leads to favorable treatment outcomes.

Generally speaking, thyroid cancer is not necessarily carcinoma in situ; some cases are confined to the in situ stage, while others have already developed infiltration or metastasis. If any abnormalities are detected, timely medical consultation is recommended. Detailed analysis is as follows:

Thyroid cancer at an early stage remains confined within the thyroid gland without breaching the basement membrane, invading surrounding tissues, or spreading to lymph nodes or distant sites. This stage is considered carcinoma in situ. These localized cases often achieve favorable treatment outcomes through surgical removal.

As the disease progresses, thyroid cancer cells may breach the basement membrane, invade surrounding tissues, or develop lymph node or distant metastases, indicating the cancer is no longer in situ. In these cases, the disease has spread further, increasing treatment difficulty and requiring a combination of therapeutic approaches to control the condition.

Once thyroid cancer is detected, prompt determination of the disease stage and cooperation with physicians to implement targeted treatment are crucial to avoid delays that could negatively impact prognosis.