Which is better for disinfection, povidone-iodine or complex iodine?

Jul 15, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
For common superficial wounds such as minor abrasions or cuts in daily life, iodophor is less irritating, effectively kills bacteria, fungi, and other pathogens, has a broad disinfection range, and is convenient to use—simply apply directly to the affected area—making it more suitable for home or general medical settings. Iodine complex contains a higher concentration of iodine, providing stronger and longer-lasting antibacterial effects, and is suitable for scenarios requiring strict asepsis, such as surgical incisions and puncture sites.

Generally, povidone-iodine is more effective for disinfecting most everyday wounds, while iodine complex is more suitable for specific medical procedures such as surgical site disinfection and is unnecessary for ordinary wounds. Detailed analysis is as follows:

For common superficial wounds such as skin abrasions and cuts, povidone-iodine is less irritating and can effectively kill bacteria, fungi, and other pathogens. It has a broad disinfecting range and is convenient to use. It can be applied directly without causing significant irritation to the wound, making it more suitable for home or general medical settings.

Iodine complex contains a higher concentration of iodine, providing stronger and longer-lasting antibacterial effects, making it suitable for areas requiring strict aseptic conditions, such as surgical incisions and puncture sites. However, when used on ordinary superficial wounds, its strong irritation may cause pain and potentially impair wound tissue healing, making it unsuitable for routine disinfection of minor injuries.

Selection should be based on wound type and disinfection requirements to avoid improper use. Those allergic to iodine should not use it, and if discomfort occurs, discontinue use immediately and seek appropriate treatment.

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