What are the causes of single fetal demise in twin pregnancies?
Generally, singleton embryonic demise in twin pregnancies may be caused by factors such as developmental differences in the embryos themselves, unequal placental allocation, chromosomal abnormalities, gestational hypertension, or chorioamnionitis. If discomfort symptoms occur, timely medical consultation and treatment at a regular hospital are recommended. Detailed explanations are as follows:
1. Developmental Differences in Embryos
One embryo in a twin pregnancy might gradually fall behind in development due to insufficient developmental potential, eventually ceasing development altogether. Regular ultrasound examinations are necessary to closely monitor the development of the surviving embryo. A balanced diet during pregnancy should be maintained to provide sufficient nutritional support for the surviving embryo, while avoiding excessive fatigue.
2. Unequal Placental Allocation
When twins share a placenta or there is unequal distribution of placental blood vessels, one embryo may receive insufficient blood and nutrients to sustain normal development. Under a doctor's guidance, enhanced prenatal monitoring should be implemented, using ultrasound to observe placental blood flow. When necessary, adjust body position as advised by the doctor to improve nutrient supply.
3. Chromosomal Abnormalities
Chromosomal number or structural abnormalities in an embryo can cause it to stop developing naturally during gestation. If this cause is diagnosed, there is no need for excessive anxiety; simply follow medical advice to regularly check the condition of the surviving embryo. Prior to the next pregnancy, both partners can undergo chromosomal testing to reduce the risk.
Elevated blood pressure in pregnant women can affect placental blood flow perfusion, making one embryo prone to embryonic demise due to insufficient blood supply. Under a doctor's guidance, medications such as labetalol tablets, nifedipine tablets, and methyldopa tablets can be used to control blood pressure. At the same time, a low-salt diet should be maintained, with regular blood pressure and urine protein monitoring.
5. Chorioamnionitis
Inflammation caused by infection of the fetal membranes can affect the embryo's living environment, possibly leading to singleton embryonic demise. Under a doctor's guidance, medications such as penicillin G sodium injection, cefotaxime sodium injection, and azithromycin dispersible tablets can be used for treatment. Close monitoring of the other embryo is necessary, with preterm termination of pregnancy considered necessary when indicated.
In daily life, pregnant women carrying twins should pay extra attention to rest and avoid strenuous exercise; maintain personal hygiene to prevent infections. Regular prenatal checkups should be conducted to promptly detect and manage abnormalities, ensuring the health of the surviving embryo.
