What causes high levels of highly sensitive thyroid-stimulating hormone (TSH)?

Jul 19, 2025 Source: Cainiu Health
Dr. Yang Chuanjia
Introduction
In general, elevated levels of sensitive thyroid-stimulating hormone (TSH) may be caused by factors such as aging, pregnancy, Hashimoto's thyroiditis, subclinical hypothyroidism, or a pituitary TSH-secreting tumor. If discomfort symptoms occur, it is recommended to seek timely diagnosis and treatment at a reputable hospital. In daily life, it is important to maintain a light and nutritionally balanced diet, avoiding excessive consumption of greasy and cold foods.

Generally, elevated levels of sensitive thyroid-stimulating hormone (sTSH) may be caused by factors such as aging, pregnancy, Hashimoto's thyroiditis, subclinical hypothyroidism, or pituitary TSH-secreting tumors. If discomfort symptoms occur, it is recommended to seek timely medical consultation and treatment at a reputable hospital. Detailed explanations are as follows:

1. Aging

With increasing age, the functions of various organs gradually decline. The regulatory function of the thyroid gland may also decrease, possibly leading to fluctuations and an increase in sTSH secretion. It is important to maintain a regular lifestyle, eat a balanced diet, and appropriately consume iodine-rich foods such as kelp and nori.

2. Pregnancy

During pregnancy, significant hormonal changes occur in a woman's body. To meet the developmental needs of the fetus, thyroid function undergoes corresponding adjustments, which may lead to elevated sTSH levels. Regular thyroid function tests should be conducted during pregnancy to closely monitor changes in related indicators.

3. Hashimoto's Thyroiditis

Hashimoto's thyroiditis is an autoimmune disease that damages thyroid tissue, leading to reduced synthesis and secretion of thyroid hormones. This triggers a feedback mechanism that increases sTSH secretion and may be accompanied by symptoms such as goiter. Under a doctor's guidance, medications such as levothyroxine sodium tablets or thyroid extract tablets can be used to supplement thyroid hormones. Excessive intake of iodine-rich foods should be avoided, and regular follow-up tests for thyroid function and related antibodies are necessary.

4. Subclinical Hypothyroidism

In subclinical hypothyroidism, thyroid hormone levels remain within the normal range, but sTSH levels are already elevated, indicating an early sign of hypothyroidism. Treatment under medical supervision with medications such as levothyroxine sodium tablets, thyroid extract tablets, or methylprednisolone tablets may be required for hormone replacement therapy.

5. Pituitary TSH-Secreting Tumor

A pituitary tumor that autonomously secretes excessive sTSH can stimulate the secretion of thyroid hormones, potentially causing symptoms such as heat intolerance, excessive sweating, and weight loss. Under medical guidance, medications such as bromocriptine mesylate tablets, cabergoline tablets, or quinagolide tablets may be used to inhibit hormone secretion by the tumor.

In daily life, maintaining a light and nutritionally balanced diet is important. Avoid consuming excessive greasy or cold foods. Choose suitable forms of exercise according to individual conditions, such as jogging or yoga, and consistently engage in physical activity to maintain good overall health.