What causes thickening of the endometrium in women?
Jul 19, 2025
Source: Cainiu Health
Dr. Zhang Lu
Introduction
Under normal circumstances, thickening of the endometrium in women may be caused by changes in the menstrual cycle, hormonal fluctuations during puberty, endocrine disorders, endometritis, polycystic ovary syndrome (PCOS), or other related factors. It is recommended to seek timely medical attention, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. In daily life, maintaining a positive mood and avoiding excessive stress or anxiety is also important.
Generally, thickening of the endometrium in women may be caused by changes in the menstrual cycle, hormonal fluctuations during puberty, endocrine disorders, endometritis, polycystic ovary syndrome (PCOS), and other factors. It is recommended to seek timely medical consultation to identify the underlying cause and receive appropriate treatment under a physician's guidance. A detailed analysis is as follows:
1. Menstrual cycle changes: Before menstruation, estrogen secreted by the ovaries continuously acts on the endometrium, causing it to thicken naturally in preparation for implantation of a fertilized egg. The endometrium becomes thinner after menstruation. This is a normal physiological phenomenon that requires no special treatment; simply monitoring the menstrual cycle is sufficient.
2. Hormonal fluctuations during puberty: In adolescent females, the hypothalamic-pituitary-ovarian axis is not yet fully mature, leading to unstable hormone secretion, which may cause endometrial thickening. As the individual ages, hormonal regulation gradually becomes regular, and symptoms typically improve spontaneously. Maintaining a regular sleep-wake cycle in daily life is recommended.
3. Endocrine disorders: Long-term熬夜 (staying up late), significant mental stress, and similar factors can lead to excessive estrogen secretion and relatively insufficient progesterone, resulting in persistent endometrial thickening, which may be accompanied by menstrual irregularities. Adjusting lifestyle habits can help alleviate these symptoms. If necessary, medications such as Modified Xiaoyao Pills, Qizhi Xiangfu Pills, or Wujibai Feng Pills may be used under medical guidance to regulate hormone levels.
4. Endometritis: Infection of the endometrium by pathogens such as bacteria causes inflammation, and the inflammatory stimulation leads to endometrial hyperemia and thickening, often accompanied by symptoms such as lower abdominal pain and increased vaginal discharge. Patients may follow medical advice to take medications such as Cefixime Dispersible Tablets, Metronidazole Tablets, or Fuyankang Tablets for treatment.
5. Polycystic ovary syndrome (PCOS): Due to abnormal endocrine metabolism leading to ovarian dysfunction, estrogen levels rise, causing endometrial thickening accompanied by symptoms such as oligomenorrhea and hirsutism. Patients may take medications such as Ethinylestradiol Cyproterone Acetate Tablets, Spironolactone Tablets, or Metformin Hydrochloride Tablets under medical supervision to alleviate symptoms. In severe cases, ovarian drilling may be performed to promote ovulation and regulate hormone levels.
In daily life, maintaining a positive mood and avoiding excessive tension and anxiety are important. Pay attention to eating a light diet and reducing intake of high-fat and high-sugar foods. Consistently engaging in moderate exercise, such as yoga or brisk walking, can help regulate the endocrine system and maintain normal endometrial health.
