Is the development of pus-filled sores on the calves related to changes in hormone levels?

Jul 29, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
When hormone levels undergo significant changes, the body's immune function may be affected, leading to abnormal sebum secretion. This can promote bacterial growth and subsequent infection, resulting in the formation of abscesses. If the occurrence of abscesses coincides with the period of hormonal fluctuations, it may be related to these changes. However, abscesses may also develop due to clear causes such as infections from traumatic injuries or improper care following insect bites, when hormone levels are stable.

Generally, significant fluctuations in hormone levels may trigger the development of abscesses on the lower leg; however, when hormone levels are stable, the association is less likely. If abnormalities occur, prompt medical attention is recommended. Detailed analysis is as follows:

When hormone levels undergo substantial changes, immune function may be affected, leading to abnormal sebum secretion and making the skin more susceptible to bacterial growth and subsequent infection, which can result in abscess formation. If the occurrence of abscesses coincides with periods of hormone fluctuation, a potential association may exist.

If hormone levels remain stable and the abscesses result from clearly identifiable external injuries infection, improper care after insect bites, or similar causes, and there are no associated endocrine abnormalities, the condition is likely unrelated to hormone level changes.

When abscesses appear on the lower leg, observe whether other physical changes occur simultaneously, record the onset time and physical condition. If the condition persists or recurs, seek timely medical evaluation to identify the underlying cause and avoid delayed treatment.

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