Will a positive HBsAb test result lead to cancer?

Jul 29, 2025 Source: Cainiu Health
Dr. Yang Ziqi
Introduction
Under normal circumstances, a positive HBsAb alone does not lead to cancer; however, the presence of other conditions such as chronic liver disease may increase the risk. A positive HBsAb indicates the presence of protective antibodies against hepatitis B in the body, demonstrating immunity to the hepatitis B virus. This marker itself has no direct association with cancer. Individuals with this profile typically have normal liver function, no other chronic diseases, and stable overall health.

Generally speaking, isolated HBsAb positivity does not lead to cancer. However, if chronic liver disease or other conditions are also present, the risk may increase. If concerned, it is recommended to seek medical advice early. Detailed analysis is as follows:

HBsAb positivity indicates the presence of protective antibodies against hepatitis B in the body, demonstrating immunity to the hepatitis B virus. This indicator itself has no direct association with cancer. If liver function is normal, no other chronic diseases exist, and overall health is stable, HBsAb positivity alone typically does not cause cancer.

If HBsAb-positive individuals also suffer from chronic hepatitis, cirrhosis, or other liver diseases, or have long-term unhealthy lifestyle habits such as excessive alcohol consumption and staying up late, these factors may damage liver cells and increase the possibility of cancerous changes. The risk in such cases stems from the underlying diseases and lifestyle habits, rather than HBsAb positivity itself.

Individuals with HBsAb positivity should undergo regular liver examinations, maintain a healthy lifestyle, and seek timely medical evaluation for any liver discomfort or abnormal liver function to reduce health risks.