What is the optimal time for liver function tests?

Aug 01, 2025 Source: Cainiu Health

Dr. Gao Jun

Introduction

In general, the optimal time for liver function tests is in the morning, and it is usually recommended to conduct the test before 9 a.m., preferably no later than 12 p.m. at noon. To ensure reliable test results, one should avoid eating after 8 p.m. the previous night, though small amounts of plain water may be consumed. On the morning of the test, you should not eat breakfast, engage in vigorous exercise, and should remain in a calm state before going to the hospital for the examination.

Generally, the optimal time for a liver function test is in the morning, and it is usually recommended to perform the test before 9 a.m., preferably no later than 12 p.m. at noon. Detailed explanations are as follows:

The optimal time for a liver function test is typically in the morning because the test requires fasting. After a night's sleep, the body is in a fasting state, and various components in the blood tend to be relatively stable, thereby more accurately reflecting the functional status of the liver. If the test is performed too late in the day, hunger may cause metabolic disturbances, leading to fluctuations in indicators such as blood glucose levels, which can affect the accuracy of the liver function test results. Additionally, in the morning, the body's physiological activities are relatively stable, and the liver's metabolic functions are also in a more consistent state, thereby minimizing interference caused by changes in circadian rhythms on the test results.

To ensure reliable test results, it is advisable to avoid eating after 8 p.m. on the night before the test, although small amounts of plain water may be consumed. On the day of the test, you should not eat breakfast or engage in vigorous physical activity, and you should remain calm before going to the hospital for the examination.

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