Can vitamin E be used for scar repair after skin grafting?

Aug 02, 2025 Source: Cainiu Health
Dr. Chen Lu
Introduction
In general, skin grafting refers to a skin transplantation procedure, and scars refer to fibrous tissue repair after wound healing. The general reference price for skin grafting is 5,000-10,000 yuan per session, and noticeable improvement is usually observed within 10-14 days. Pain and infection may occur after surgery. During scar recovery following skin grafting, vitamin E can be used as an adjunctive treatment, although its effectiveness is not well established, and caution is advised in its use.

Generally, skin grafting refers to skin transplantation surgery, and scars refer to cicatrix formation. The general reference price for skin transplantation surgery is 5000-10000 yuan per session, and some improvement is usually noticeable within 10-14 days after surgery. Pain, infection, and other conditions may occur postoperatively. Vitamin E can be used as an adjunctive method for scar repair after skin grafting, but its effectiveness is not well established, and caution should be exercised in its use. Detailed analysis is as follows:

Vitamin E is a lipid-soluble antioxidant that, theoretically, may assist in maintaining skin barrier function by reducing oxidative skin damage and improving local microcirculation, and may have moisturizing and softening effects on early stable scars. However, clinical studies have shown a lack of clear evidence for its effectiveness in lightening scars or inhibiting scar hyperplasia. Additionally, some individuals may experience skin irritation or allergic reactions after topical application. Especially during the critical healing phase of early post-grafting scars, the skin barrier is weak, and indiscriminate use of vitamin E might interfere with the healing process.

When using vitamin E, note that it is only suitable for use on scars that are in the stable phase. Prior to application, a small patch test on healthy skin is recommended to confirm no allergic reaction occurs. Then gently apply it to the scar area without vigorous rubbing. If redness, swelling, exudation, or significant scar hyperplasia occurs, discontinue use and seek medical attention promptly.

It should be noted that consultation with a physician is recommended before using vitamin E to avoid causing discomfort. In addition, maintaining dryness and cleanliness of the skin before application is important to reduce the risk of infection.

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