Can Rehmannia glutinosa, Astragalus complanatus, and Paeonia lactiflora regulate the endocrine system?

Aug 04, 2025 Source: Cainiu Health

Dr. Sun Lianqing

Introduction

Under normal circumstances, Sh熟地黄 (Rehmannia glutinosa), Sha Yuan Zi (Astragalus complanatus), and Bai Shao (Paeonia lactiflora) can help regulate the endocrine system, but they should be used under the guidance of a TCM practitioner. When regulating the endocrine system, the proportions of the herbs should be adjusted according to individual body constitutions. For individuals with yin deficiency constitution, the dosage of Sh熟地黄 can be appropriately increased, while those with significant liver qi stagnation can have a higher proportion of Bai Shao. Sh熟地黄 is rich and sticky in nature; long-term use should be combined with spleen-strengthening ingredients to prevent impairment of spleen and stomach function.

Generally, Rehmannia glutinosa (Sh熟地黄), Astragalus complanatus (Sha Yuan Zi, 沙苑子), and Paeonia lactiflora (Bai Shao, 白芍) can help regulate the endocrine system, but they should be used under the guidance of a TCM practitioner. A detailed explanation is as follows:

Rehmannia glutinosa nourishes the yin of the liver and kidney. Sufficient kidney yin helps maintain the stability of the hypothalamic-pituitary-target gland axis, providing a foundation for endocrine balance. Astragalus complanatus tonifies the kidney and consolidates essence, while also benefiting the liver. It enhances the functions of the liver and kidney; as the liver governs the free coursing of qi, it can regulate the circulation of qi and blood and promote hormonal balance. Abundant kidney essence supports the normal functioning of the endocrine system. Paeonia lactiflora nourishes the blood and soothes the liver, helping to alleviate endocrine disorders caused by liver qi stagnation. Its blood-nourishing effect provides material support for hormone synthesis, while its soothing properties help prevent fluctuations in the endocrine system due to excessive liver qi. Together, these three herbs work synergistically by nourishing the liver and kidney, regulating liver qi, and replenishing yin and blood, thereby effectively regulating the endocrine system.

When regulating the endocrine system, the proportions of the herbs should be adjusted according to individual constitutions. Patients with yin deficiency constitution may appropriately increase the dosage of Rehmannia glutinosa, while those with significant liver qi stagnation may increase the proportion of Paeonia lactiflora. Rehmannia glutinosa is nourishing and greasy in nature, so for long-term use, it should be combined with spleen-strengthening ingredients to prevent impairment of spleen and stomach function. During the course of use, a regular lifestyle and balanced diet should be maintained, avoiding late nights and significant emotional fluctuations that may interfere with the therapeutic effects. If endocrine disorders are severe, professional medical treatment should be sought, and reliance solely on this herbal combination is not recommended.

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