Is there a difference in the normal range of uric acid between males and females?

Generally, the normal range of uric acid differs between men and women. The detailed analysis is as follows:

Uric acid is the end product of purine metabolism and is primarily excreted through the kidneys. Its level is influenced by factors such as age, gender, and diet. The normal range for serum uric acid in men is typically 208–416 μmol/L. For women, the normal range is 149–358 μmol/L, although it may approach male levels after menopause, generally not exceeding 420 μmol/L. These differing normal ranges indicate that men and women face varying probabilities of related health risks. For example, the incidence of gout in men is generally higher than in women, partly due to higher uric acid levels in men.

Maintaining healthy lifestyle habits, such as reducing intake of high-purine foods, drinking plenty of water, and avoiding alcohol, can help keep uric acid levels within the normal range. If uric acid levels become abnormal, it is advisable to consult a doctor for individualized assessment.