What is the normal value of serum high-density lipoprotein cholesterol?

Aug 18, 2025 Source: Cainiu Health
Dr. Tian Hongbo
Introduction
There is a certain degree of difference between genders, with the normal range for males being relatively slightly lower, typically between 1.04-1.55 mmol/L; females, influenced by hormones and other factors, have a somewhat higher normal range, generally between 1.16-1.55 mmol/L, which may gradually approach male levels after menopause. Variations in testing methods and laboratories can also cause slight fluctuations in reference ranges.

Generally, the normal range of serum high-density lipoprotein cholesterol (HDL-C) varies among different populations, and for adults, it is typically between 1.04 and 2.07 mmol/L. If abnormal levels are detected, timely medical consultation is recommended. Detailed analysis is as follows:

There are certain differences between genders, with the normal range for males being relatively lower, usually between 1.04 and 1.55 mmol/L; females, influenced by hormones and other factors, have a slightly higher normal range, generally between 1.16 and 1.55 mmol/L. After menopause, HDL-C levels may gradually approach those seen in males.

Differences in testing methods and laboratories can also cause slight variations in reference ranges. Some institutions set the lower limit of normal at 0.91 mmol/L and the upper limit at 2.2 mmol/L. The specific reference values are usually indicated on the test report, and individuals can determine whether their results are within the normal range by referring to these values.

Before testing, it is important to maintain regular eating habits and a normal routine, and avoid strenuous exercise, alcohol consumption, or other behaviors that may affect the results. If the measured value falls outside the normal range, further lipid profile tests are recommended to obtain a comprehensive assessment, and any necessary adjustments should be made under the guidance of a physician.