What is the normal value for Helicobacter pylori?

Generally, there is no unified standard for the normal value of Helicobacter pylori, and the determination depends on the different testing methods used. Commonly used clinical methods include carbon-13 and carbon-14 urea breath tests, as well as histological examination of biopsy samples obtained during gastroscopy, each having its own reference ranges. Exceeding these ranges often suggests a possible infection. Detailed analysis is as follows:

The carbon-13 urea breath test is a common non-invasive testing method, with a typical reference value of 0-4 dpm. If the measured value falls within this range, it indicates no infection or a very low level of infection. If the value exceeds 4 dpm, it suggests a possible Helicobacter pylori infection. The reference value for the carbon-14 urea breath test is generally 0-100 dpm; values below 100 dpm are considered negative, while values above 100 dpm are considered positive, and whether treatment is needed should be assessed based on symptoms. Histopathological examination of biopsy samples during gastroscopy determines infection by identifying the presence of Helicobacter pylori in the gastric mucosa. The absence of bacterial detection is considered normal.

Prior to Helicobacter pylori testing, medications such as antibiotics and proton pump inhibitors that may interfere with test results should be discontinued as instructed. After testing, results should be interpreted according to the reference range of the specific testing method used. If infection is indicated, a standardized treatment plan should be followed, along with attention to dietary hygiene and minimizing gastric irritation.