What medications can be taken for low high-density lipoprotein cholesterol?
Sep 03, 2025
Source: Cainiu Health
Dr. Tian Hongbo
Introduction
Pravastatin sodium tablets belong to the statin class of drugs. By inhibiting cholesterol synthesis, they indirectly increase high-density lipoprotein cholesterol levels while reducing low-density lipoprotein cholesterol. They are suitable for individuals with mixed dyslipidemia and should be taken at the prescribed dosage under medical supervision. Simvastatin tablets regulate lipid metabolism, promote the synthesis of high-density lipoprotein cholesterol, and improve lipid profile.
Low levels of high-density lipoprotein cholesterol (HDL-C) can generally be managed under a physician's guidance with medications such as pravastatin sodium tablets, simvastatin tablets, pitavastatin calcium tablets, ezetimibe tablets, and fenofibrate capsules. Detailed explanations are as follows:
1. Pravastatin Sodium Tablets: This medication belongs to the statin class of drugs. It works by inhibiting cholesterol synthesis, indirectly increasing HDL-C levels while lowering low-density lipoprotein cholesterol (LDL-C). It is suitable for individuals with mixed dyslipidemia and should be taken according to the prescribed dosage under medical supervision.
2. Simvastatin Tablets: As a lipid-lowering statin drug, it regulates lipid metabolism, promotes HDL-C synthesis, and improves lipid disorders. It is commonly used for primary hypercholesterolemia accompanied by low HDL-C levels. Liver function should be monitored during treatment.
3. Pitavastatin Calcium Tablets: This drug inhibits cholesterol synthesis in the liver, increases HDL-C levels, and has minimal impact on blood glucose. It is suitable for patients with dyslipidemia combined with elevated blood glucose levels and must be used strictly according to medical instructions.
4. Ezetimibe Tablets: It works by inhibiting intestinal cholesterol absorption and is often used in combination with statins to synergistically increase HDL-C levels. It is suitable for patients who do not respond adequately to statin monotherapy and should be used under physician guidance.
5. Fenofibrate Capsules: This medication belongs to the fibrate class. It activates lipoprotein lipase, promoting HDL-C metabolism and synthesis. It is particularly suitable for patients with high triglycerides combined with low HDL-C levels. Regular lipid profile monitoring is required during treatment.
In daily life, in addition to pharmacological treatment, a low-fat diet should be maintained, with increased consumption of vegetables, fruits, nuts, and other foods rich in unsaturated fatty acids.
