What causes the growth of filiform warts?

Sep 05, 2025 Source: Cainiu Health
Dr. Liu Wenmin
Introduction
Under normal circumstances, the development of filiform warts may be caused by factors such as weakened skin barrier function, prolonged friction on localized skin areas, infection with low-risk types of human papillomavirus (HPV), spread of flat warts, or evolution from common warts. It is recommended to seek timely medical attention, identify the underlying cause, and undergo symptomatic treatment under a doctor's guidance. In daily life, it is important to maintain skin cleanliness, avoid scratching affected areas with hands, and prevent the spread of the virus.

Generally, the development of filiform warts may be caused by factors such as weakened skin barrier function, prolonged friction on localized skin areas, infection with low-risk types of human papillomavirus (HPV), the spread of flat warts, or the evolution of common warts. It is recommended to seek timely medical attention to determine the underlying cause and undergo appropriate treatment under a doctor's guidance. Detailed explanations are as follows:

1. Weakened skin barrier function: Thin stratum corneum and reduced sebaceous gland secretion make the skin more susceptible to pathogen invasion, increasing the likelihood of developing filiform warts. Daily skincare should include proper moisturization using gentle moisturizing lotions. Frequent use of exfoliating products should be avoided to reduce skin irritation.

2. Prolonged friction on localized skin: Skin on areas such as the neck and eyelids may experience long-term friction from clothing collars, eyeglass frames, etc., leading to skin damage, which provides an entry point for pathogens. It is advisable to wear loose, soft clothing and adjust the position of eyeglass frames to reduce localized skin friction.

3. Infection with low-risk types of human papillomavirus: Infection of the skin with low-risk HPV types such as HPV 2, 4, and 7 can cause abnormal proliferation of epidermal cells, resulting in the formation of filiform warts. Patients may use medications such as recombinant human interferon α2b gel, imiquimod cream, or fluorouracil ointment as directed by a physician.

4. Spread of flat warts: Flat warts are caused by HPV infection. If left untreated, the virus may spread to surrounding skin areas and gradually develop into filiform warts. In addition to the antiviral medications mentioned above, cryotherapy may be performed under a doctor's supervision, using low temperatures to destroy wart tissue and promote its removal.

5. Evolution of common warts: Common warts initially appear as rough papules. If left untreated for a long time, some may gradually evolve into filiform projections, forming filiform warts. Patients may undergo laser therapy under medical guidance to remove the warts using high-energy heat. Additionally, medications such as salicylic acid ointment, tretinoin cream, or tazarotene gel may be used as adjunctive treatments.

In daily life, it is important to maintain skin cleanliness and avoid scratching affected areas with hands to prevent viral spread. Personal hygiene should also be emphasized—personal items such as towels and basins should not be shared with others to reduce the risk of cross-infection.

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