Does ankylosing spondylitis have a hereditary component?

Generally, whether ankylosing spondylitis is hereditary needs to be determined according to the disease's characteristics. This condition does show a certain genetic predisposition; individuals with a family history of the disease have a relatively higher risk of developing it. However, it is not absolutely hereditary, and people without a family history may also develop the condition due to other factors. Detailed analysis is as follows:

If there are individuals with ankylosing spondylitis in the family, especially if close relatives are affected, the probability of other family members developing the condition will be higher than that of the general population. This is because the disease is associated with specific genes that may be passed on to offspring, increasing the likelihood of developing the condition. However, merely carrying these genes does not guarantee the onset of the disease, as other factors must also play a role.

If there is no family history of ankylosing spondylitis, individuals in the general population may still develop the condition. Aside from genetic factors, long-term exposure to damp and cold environments, recurrent intestinal or urinary tract infections, and abnormal immune function can all potentially trigger ankylosing spondylitis.

To reduce the risk of developing the condition or to delay its progression, regardless of family history, proper health management is essential. Daily attention should be given to maintaining a regular routine and avoiding excessive fatigue. It is also important to stay warm and avoid dampness, and to avoid prolonged exposure to cold and humid environments.