What should be done for a drug allergy rash?

Generally, drug allergy rashes may be caused by individual allergic constitution, improper dosage or duration of medication, direct sensitization by the drug, sensitization by drug metabolites, or coexisting skin conditions. It is recommended to seek medical attention promptly, identify the underlying cause, and then improve symptoms under a doctor's guidance through general management, medication, and other approaches. The specific analysis is as follows:

1. Individual allergic constitution: Some people have naturally sensitive immune systems, making them prone to allergic reactions—including rashes—when exposed to certain medications. The suspected allergenic drug should be discontinued immediately. Patients should record the name of the allergenic drug to avoid future use, maintain skin cleanliness, wear loose cotton clothing, and minimize friction or irritation on the rash.

2. Improper dosage or treatment duration: Excessive dosing or prolonged use increases the risk of drug sensitization and may trigger rashes. Medication dosage and duration must strictly follow medical advice; patients should not adjust doses on their own. Mild rashes can be treated with topical calamine lotion to relieve itching, while monitoring for any changes in the rash.

3. Direct drug sensitization: Certain drugs such as penicillins, cephalosporins, and sulfonamides directly stimulate the immune system, causing allergic rashes, often accompanied by itching. Patients should take antihistamines such as cetirizine hydrochloride tablets, loratadine capsules, or ebastine tablets as prescribed. Scratching should be avoided to prevent skin damage and secondary infection.

4. Sensitization by drug metabolites: Metabolic byproducts of certain drugs may be allergenic, leading to delayed-type allergic rashes that appear later. In such cases, corticosteroids such as methylprednisolone tablets, dexamethasone tablets, or prednisone tablets should be used under medical supervision to suppress the allergic reaction.

5. Coexisting skin conditions: Individuals with pre-existing skin diseases such as eczema or dermatitis have compromised skin barriers, making them more susceptible to developing or worsening drug-induced allergic rashes. The underlying skin condition should be actively treated first, using medications such as hydrocortisone butyrate cream, mometasone furoate cream, or tacrolimus ointment as directed by a physician to promote rash resolution.

In daily life, maintain a light diet, avoid spicy foods, seafood, and other allergen-triggering foods that may worsen symptoms, and consume more fresh fruits and vegetables to supplement vitamins. Keep indoor areas well-ventilated and avoid exposure to other allergens such as pollen and dust mites. Comprehensive care can support the recovery of healthy skin.