Will low progesterone in a subsequent pregnancy occur after a miscarriage due to low progesterone?

Oct 15, 2025 Source: Cainiu Health
Dr. Zhang Lu
Introduction
In general, having low progesterone levels during a miscarriage does not necessarily mean that progesterone will be low in the next pregnancy. Whether low progesterone occurs again depends on the physical condition during each pregnancy and the specific underlying causes, so it cannot be directly assumed. Women with a history of miscarriage due to low progesterone are advised to undergo relevant medical examinations before planning the next pregnancy, to identify the cause of the previous low progesterone and receive targeted treatment or调理 (regulation).

In general, having low progesterone levels leading to miscarriage does not necessarily mean that progesterone will also be low in a subsequent pregnancy. Whether low progesterone occurs again depends on the physical condition during each pregnancy and the specific cause of the previous low progesterone; therefore, it cannot be directly assumed. The detailed analysis is as follows:

If the previous low progesterone was caused by temporary factors—such as abnormal ovulation during that cycle, transient luteal phase deficiency, or stress and excessive fatigue during pregnancy affecting hormone secretion—then after adjusting the body's condition, ovarian and luteal function may return to normal in the next pregnancy. Consequently, progesterone levels would likely remain within the normal range, and low progesterone may not recur.

However, if the previous low progesterone resulted from persistent underlying conditions—such as diminished ovarian reserve, polycystic ovary syndrome (PCOS), thyroid dysfunction, or unresolved diseases affecting hormone production like endometriosis—these issues may persist in a future pregnancy and could again lead to insufficient progesterone production, resulting in low progesterone levels and thereby increasing the risk of miscarriage.

Therefore, women with a history of miscarriage due to low progesterone are advised to undergo relevant medical evaluations before planning the next pregnancy, to identify the cause of the prior progesterone deficiency and receive targeted treatment. After becoming pregnant, they should also begin monitoring progesterone levels early. If low progesterone is detected, timely interventions such as progesterone supplementation should be initiated under medical supervision to reduce the risk of miscarriage and support a stable pregnancy.