Why does neonatal jaundice occur when the mother has type O blood?

Under normal circumstances, neonatal jaundice in mothers with blood type O may be caused by characteristics of neonatal bilirubin metabolism, improper breastfeeding, ABO blood group incompatibility hemolytic disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, congenital biliary atresia, and other reasons. If related symptoms occur, it is recommended to seek timely medical evaluation and treatment at a正规 hospital. The specific analysis is as follows:

1. Characteristics of Neonatal Bilirubin Metabolism

The liver function of newborns is immature and has weak bilirubin metabolism capacity, making physiological jaundice more likely to occur. Enhance feeding to promote defecation, increase sun exposure, and closely monitor changes in jaundice.

2. Improper Breastfeeding

Inadequate feeding leads to reduced bowel movements in newborns, resulting in impaired bilirubin excretion. Increase feeding frequency, ensure sufficient milk intake, and supplement with formula milk if necessary to promote bilirubin elimination through feces.

3. ABO Hemolytic Disease Due to Blood Type Incompatibility

An antigen-antibody reaction occurs between a mother with blood type O and a fetus with blood type A or B, leading to destruction of fetal red blood cells and subsequent jaundice. Under medical guidance, medications such as human immunoglobulin injection, albumin injection, and phenobarbital sodium injection may be used. Severe cases may require exchange transfusion therapy.

4. Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

Newborns lack this enzyme, leading to increased red blood cell destruction upon exposure to triggers. Avoid exposure to fava beans and certain drugs. Under medical supervision, treatments may include sodium bicarbonate injection, oral rehydration salts III, and vitamin C injection. Severe cases may require blood transfusion.

5. Congenital Biliary Atresia

Abnormal bile duct development obstructs bile drainage, causing bilirubin to reflux into the bloodstream. Prompt Kasai procedure is required to reconstruct the bile duct. Postoperative medication and care should follow medical advice. If surgical outcomes are unsatisfactory, liver transplantation should be considered.

In daily life, strengthen newborn feeding to ensure adequate nutrition; closely observe the onset time, severity, and resolution of jaundice; avoid exposing the newborn to substances that may trigger hemolysis; and conduct regular newborn check-ups for early detection and early intervention.