酒精肝What指标偏高
Oct 22, 2025
Source: Cainiu Health
Dr. Gao Jun
Introduction
一般情况下，酒精肝Patient在Examination中常出现血清丙氨酸氨基转移酶、血清天冬氨酸氨基转移酶、γ-谷氨酰转肽酶、总胆红素、甘油三酯等指标偏高。Recommendation酒精肝Patient及时戒酒，避免继续损伤Liver，同时保持清淡Diet，减少高脂肪、高糖食物摄入。
In general, patients with alcoholic liver disease often show elevated levels of serum alanine aminotransferase, serum aspartate aminotransferase, gamma-glutamyl transferase, total bilirubin, triglycerides, and other indicators during medical examinations. The specific analysis is as follows:
1. Serum alanine aminotransferase (ALT): This indicator is primarily found within liver cells. When alcohol damages hepatocytes, ALT is released into the bloodstream, leading to elevated levels. In mild alcoholic liver disease, ALT may only slightly increase; however, as liver cell damage worsens, the elevation becomes more pronounced, reflecting the degree of hepatic inflammation.
2. Serum aspartate aminotransferase (AST): This enzyme is also abundantly present in liver cells. Alcohol-induced hepatocyte damage causes its release into the blood, resulting in elevated levels. In alcoholic liver disease, AST elevation typically occurs alongside increased ALT. In severe cases, AST levels may rise higher than ALT.
3. Gamma-glutamyl transferase (GGT): This indicator is highly sensitive to alcohol-related damage. Alcohol consumption easily enhances its activity, leading to elevated blood levels. Even in mild alcoholic liver disease, GGT may significantly increase and tends to normalize slowly. Therefore, it serves as an important marker for both diagnosis and monitoring of disease progression.
4. Total bilirubin: Bilirubin is primarily metabolized by the liver. When alcoholic liver disease damages hepatocytes, bilirubin metabolism is impaired, causing accumulation and elevated levels in the blood. Elevated total bilirubin may be accompanied by jaundice of the skin and sclera. The degree of elevation correlates with the severity of liver cell injury—the greater the damage, the more pronounced the increase in bilirubin.
5. Triglycerides: Long-term alcohol consumption disrupts the liver’s fat metabolism, leading to fat accumulation in hepatocytes and increasing triglyceride synthesis while reducing clearance in the bloodstream, thereby causing elevated triglyceride levels. Hypertriglyceridemia is not only a common feature of alcoholic liver disease but may also exacerbate fatty liver changes.
Patients with alcoholic liver disease are advised to quit alcohol immediately to prevent further liver damage, maintain a light diet, reduce intake of high-fat and high-sugar foods, and engage in mild physical activities such as walking or jogging to support liver function recovery.
