What are the effects of teriparatide injection?

Teriparatide injection is a medication used to treat osteoporosis, with effects including promoting osteoblast activity, increasing bone mineral density, reducing fracture risk, improving bone microstructure, and alleviating bone pain. It must be used under professional medical supervision. If severe bone pain, nausea, vomiting, or allergic reactions occur during treatment, medical attention should be sought promptly.

1. Promotes osteoblast activity: As a parathyroid hormone analog, teriparatide directly acts on osteoblasts to enhance their proliferation and function, stimulating new bone formation and accelerating bone tissue generation, thereby supporting the repair of skeletal structure.

2. Increases bone density: By enhancing osteoblast activity and reducing bone resorption, teriparatide promotes continuous accumulation of bone mass, gradually increasing bone mineral density in key areas such as the lumbar spine and hip. This improves bone strength and reduces risks associated with bone loss.

3. Reduces fracture risk: By increasing bone density and improving bone strength, teriparatide lowers the incidence of both vertebral and non-vertebral fractures in patients with osteoporosis, particularly showing significant benefits in high-risk individuals with a prior history of fractures.

4. Improves bone microstructure: Teriparatide helps regulate the microscopic architecture of bone tissue by increasing trabecular bone number and improving trabecular connectivity, reducing micro-damage in bone, enhancing overall biomechanical performance, and strengthening the bone's resistance to fracture.

5. Alleviates bone pain: For some patients experiencing bone pain due to osteoporosis, teriparatide can indirectly reduce pain symptoms by improving bone density and repairing bone structure, thus enhancing daily mobility and quality of life.

In daily use, patients should take the medication exactly as prescribed—on time and in the correct dosage—without adjusting the dose independently. Mild physical activities such as walking or tai chi are recommended during treatment. Adequate dietary intake of calcium and vitamin D, regular sleep patterns, and measures to prevent falls and other accidents that could lead to fractures are also essential.