Will metastasis occur during chemotherapy?
In general, whether metastasis occurs during chemotherapy depends on the specific type of cancer and the response to treatment. If any discomfort arises, it is recommended to seek medical attention promptly. The detailed analysis is as follows:

If the cancer type is highly sensitive to chemotherapy, tumor lesions significantly shrink after treatment, tumor cell activity is effectively suppressed, and the patient is in good physical condition and able to tolerate a full course of chemotherapy, the likelihood of metastasis during chemotherapy is relatively low. Standardized chemotherapy can eliminate most rapidly proliferating tumor cells, reducing the chance of tumor cells spreading to other organs and thereby delaying or preventing metastasis.
However, if the cancer type has low sensitivity to chemotherapy, or if undetected micrometastases already exist prior to treatment, or if the patient is too weak to complete the full dose of chemotherapy, tumor cells may continue to proliferate and spread. In such cases, metastasis remains possible during chemotherapy. Some tumor cells may develop resistance to chemotherapeutic agents, survive throughout treatment, and lead to new metastatic lesions.
During chemotherapy, regular imaging examinations and tumor marker tests are necessary to monitor changes in the tumor. Maintaining a regular作息 (daily routine), balanced diet, and adequate nutritional intake can enhance the body's tolerance to chemotherapy. If symptoms such as unexplained pain, sudden weight loss, or worsening fatigue occur, they should be reported to the doctor immediately to rule out signs of metastasis. It is essential to strictly follow medical advice and complete the full chemotherapy regimen without interrupting treatment prematurely, to avoid compromising efficacy and increasing the risk of metastasis.