Does it matter if I'm not a virgin when getting the 9-valent HPV vaccine?

Being not a virgin has no impact on receiving the 9-valent HPV vaccine; the protective effect of the vaccine is not directly related to virginity. If you have a need for vaccination or experience cervical discomfort, it is recommended to seek medical advice promptly.

The 9-valent HPV vaccine targets nine high-risk and low-risk HPV subtypes and works by stimulating the body to produce protective antibodies. Non-virgins may have already been exposed to some HPV subtypes, but it is rare for someone to be infected with all nine subtypes. The vaccine can still provide protection against the subtypes not yet contracted, thereby reducing the risk of future infections.

In terms of vaccination benefits, even individuals who are sexually active should still receive the 9-valent HPV vaccine. Sexual intercourse is the primary route of HPV transmission, and infections may occur without obvious symptoms. The vaccine helps fill gaps in immune protection that may have been missed previously, reducing the likelihood of developing cervical intraepithelial neoplasia, cervical cancer, and other related diseases—particularly beneficial for women within the recommended age range.

In daily life, it's important to maintain good sexual hygiene, avoid having multiple sexual partners, undergo regular cervical screenings, maintain a regular sleep schedule to strengthen immunity, minimize the risk of HPV infection, and promote overall reproductive health.