Can uterine polyps and HPV58 positive lead to precancerous lesions?

Most uterine polyps do not lead to precancerous changes; however, persistent infection with HPV type 58 increases the risk of cervical intraepithelial neoplasia, though not all infected individuals will develop precancerous lesions. If uterine polyps show abnormal growth or if HPV58 positivity is accompanied by abnormal cervical bleeding, prompt medical consultation is recommended.

Uterine polyps are mostly benign endometrial or cervical polyps, associated with fluctuations in estrogen levels and inflammatory stimulation. They often cause no noticeable symptoms and are only incidentally discovered during examinations, requiring regular monitoring. Only a small proportion of adenomatous polyps, due to active cell proliferation, may slowly progress over time. Their nature should be confirmed via pathological examination, and timely intervention can prevent malignant transformation.

HPV type 58 is classified as a high-risk human papillomavirus. Infections lasting more than 12 months can damage cervical epithelial cells, leading to abnormal cell proliferation and progression to low-grade or high-grade cervical intraepithelial neoplasia (precancerous lesions). However, the body's immune system typically clears the virus spontaneously within 1–2 years. Only individuals with weakened immunity and persistent viral infection need to be vigilant about the development of precancerous changes.

In daily life, maintaining a regular作息 to enhance immunity, practicing proper genital hygiene, avoiding unhygienic sexual practices, reducing cervical irritation, undergoing regular gynecological exams and HPV testing, and recording any abnormal physical symptoms are essential for early detection and timely intervention.