What are the side effects of levofloxacin lactate tablets?

Generally, levofloxacin lactate tablets, as a quinolone antibiotic, commonly cause side effects primarily affecting the gastrointestinal tract, skin, nervous system, musculoskeletal system, and urinary system. Most of these side effects are mild and tend to resolve after discontinuation of the drug. Specific adverse reactions include gastrointestinal discomfort, skin allergic reactions, neurological symptoms, musculoskeletal injuries, and urinary system abnormalities. Detailed information is as follows:

1. Gastrointestinal discomfort: This is the most common side effect, manifesting as nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Symptoms typically occur early in treatment and are usually mild and tolerable. However, severe diarrhea may lead to dehydration or electrolyte imbalances, so it is important to promptly replenish fluids and electrolytes.

2. Skin allergic reactions: Some individuals may develop rashes, itching, or urticaria after taking the medication. In rare cases, severe allergic dermatitis may occur, such as lupus-like reactions characterized by skin redness, blisters, and intensified itching.

3. Neurological symptoms: A minority of people may experience dizziness, headache, drowsiness, or fatigue. Occasionally, restlessness, insomnia, or anxiety may occur. In very rare cases, seizures may be triggered. Patients should avoid activities requiring high concentration—such as driving or working at heights—during treatment.

4. Musculoskeletal injury: The drug may cause joint pain, muscle soreness, or tendonitis. Tendon rupture is rare but possible. If severe muscle or joint pain occurs during treatment, the drug should be discontinued immediately, and physical activity—especially strenuous exercise—should be avoided.

5. Urinary system abnormalities: A small number of individuals may experience increased urinary frequency, urgency, or dysuria. Some may show abnormal kidney function indicators. Patients with pre-existing kidney disease should have their renal function monitored regularly during treatment to avoid increasing the burden on the kidneys.

It is also important to observe contraindications and precautions. The drug is contraindicated in individuals under 18 years of age, pregnant women, and breastfeeding women. It should be used with caution in patients with a history of epilepsy or severe liver or kidney dysfunction. Alcohol consumption should be avoided during treatment. Dosage and duration must strictly follow medical instructions to ensure both safety and efficacy.